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Vacuum Technology in Research & Development

As a company trusted by scientific institutions and universities worldwide, Pfeiffer Vacuum+Fab Solutions provides complete vacuum systems that support research in labs and large-scale scientific facilities worldwide.

From material science to particle physics and space technologies, our solutions create stable, clean environments so you can focus on results, not setup.

Powering research across disciplines

Whether you are developing the next generation of semiconductors, exploring quantum materials, or running high-energy physics experiments, different pressure levels address specific research needs:

  • Rough to medium vacuum supports common lab processes such as glove box, Schlenk lines, and drying.
  • High to ultra-high vacuum (UHV) is essential for surface science, plasma physics, and cryogenic research.
  • UHV enables precision in particle accelerators, surface analysis, and high-energy physics.

But vacuum is more than just selecting the right pump. The system must also be properly connected, precisely measured, and continuously analyzed. From instrumentation and sensor integration to residual gas analysis and leak detection, Pfeiffer provides complete vacuum solutions that ensure your setup performs reliably and efficiently.

Vacuum applications in R&D - from big science to basic research.

Particle accelerators

From synchrotron light sources to spallation sources and free-electron lasers, particle accelerators require stable ultra-high vacuum (UHV) to maintain beam integrity, reduce scattering, and ensure reproducible results. Even minor fluctuations in pressure or contamination can compromise data or lead to costly interruptions.

Pfeiffer delivers high-performance vacuum solutions engineered to meet these demanding conditions: Turbomolecular vacuum pump units with low vibration and magnetic shielding for reliable operation in extreme environments such as radiation zones, all-metal-sealed components for long-term stability, and diagnostic tools for real-time pressure monitoring. Our systems are proven in leading research facilities and designed for seamless integration into complex, modular beamline infrastructures.

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Vacuum equipment for space research

Space simulation demands stable high to ultra-high vacuum environments that replicate orbital conditions with high accuracy and long-term stability. Key challenges include minimizing outgassing, maintaining uniform pressure profiles, enabling thermal cycling, and ensuring stable environmental conditions for sensitive instrumentation.

Pfeiffer provides fully integrated solutions for space research, combining high-performance turbopumps, precise instrumentation, and custom-engineered vacuum chambers. Our chambers are optimized for ultra-low background contamination and offer optional heating or cooling. They also feature high-grade surface finishes with light-absorbing coatings to simulate the darkness of space.

Our technologies are used in major test facilities worldwide, including a long-standing partnership with the German Aerospace Center (DLR).

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Laboratory vacuum

Laboratories rely on quiet, clean, and precisely controlled vacuum systems – whether for sample preparation, lyophilization, or analytical instrumentation such as mass spectrometry. Key requirements include stable pressure control, low noise levels, and compact design.

Pfeiffer provides solutions combining oil-free scroll vacuum pumps, high-vacuum turbopumps, and precision gauges. These technologies support sensitive applications in confined lab spaces while ensuring reliable, reproducible results across a wide range of scientific disciplines.

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More applications across research disciplines

Research does not stop at big installations or standard lab setups. Across many markets, vacuum conditions are critical for maintaining precision, stability, and reproducibility. Pfeiffer supports these environments by addressing the specific challenges researchers face:

Cryogenics

Avoiding thermal losses and ensuring vacuum insulation stability are key to achieving reliable results in low-temperature and superconductivity experiments.

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Lyophilization (freeze drying)

Reproducible drying results depend on stable pressure control – especially during critical sublimation phases in pharmaceutical and life science research.

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Photonics research

High-precision optical setups require ultra-clean, particle-free environments. Even minor contamination can compromise optical alignment or coating performance.

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Plasma physics

Generating and sustaining stable plasma conditions calls for robust vacuum control and fast responsiveness during dynamic experimental cycles.

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Central vacuum systems

Multi-user labs and shared research facilities need reliable, consistent vacuum supply across varying applications – without compromise in flexibility or uptime.

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Preconfigured packeges for Research & Development

Complete, ready-to-use solutions for science and engineering

Our R&D packages bundle vacuum pumps, controllers, cables, and accessories into preconfigured kits – making setup quick, dependable, and frustration-free. Everything is matched so even users unfamiliar with vacuum, like beginning students or new customers, can get started right away. You benefit from:

  • Fast delivery: All products are in stock and ready to ship
  • Clear documentation: Full technical data and scope of delivery at a glance
  • Easy selection of the right size: Our online vacuum calculator guides you to the right setup
  • Trusted: The most commonly used packages on the market

Four package lines to match your needs:

Scroll vacuum pump packages

Range: Rough to medium vacuum

The package without pressure sensor includes an oil-free HiScroll scroll vacuum pump, mains cable, and exhaust silencer. Ideal for quiet, vibration-free operation in standard lab environments.

The package with integrated pressure sensor adds an integrated pressure sensor and a control unit. This enables the user to optimize power consumption and conveniently monitor vacuum levels – ensuring even quieter, more efficient, and more reliable performance.

Explore HiScroll packages

Turbopump packages

Range: High to ultra-high vacuum (requires a separate backing pump, e.g., HiScroll)

Combines a HiPace turbopump with a backing pump, electrical controller, all interface cables, and mounting accessories – perfect for high and ultra-high vacuum applications with flexible integration needs.

Explore HiPace packages

HiCube Neo packages

Range: High to ultra-high vacuum (complete solution with turbopump + backing pump)

A mobile HV- and UHV- vacuum pump unit featuring a HiPace turbopump, a backing pump, complete control system, and housing. Available in desktop or floor-standing configurations.

Explore HiCube Neo packages

Measurement packages

Vacuum gauges deliver precise and stable pressure measurement across a wide vacuum range. Each package combines a DigiLine or ActiveLine gauge with an OmniControl unit and all necessary cables, giving you a complete, ready-to-use solution.

Explore DigiLine packages Explore ActiveLine packages

Need a quick comparison or want to see all variants at a glance?
Simplify your planning, accelerate your setup, and stay focused on what matters: your research.

Discover our packages

Our R&D product portfolio

  • ath_m_turbopumps

    Turbomolecular vacuum pumps

    Essential for achieving high and ultra-high vacuum levels for advanced research and industrial applications.

    Turbopumps
  • scroll_pump_hiscroll_1

    Scroll vacuum pumps

    Oil-free backing pumps ideal for clean, quiet operation in laboratories and compact setups.

    Scroll pumps
  • diaphragm_pumps_mvp_neo

    Diaphragm vacuum pumps

    Compact and easy to operate – perfect for rough vacuum applications like filtration or degassing.

    Diaphragm pumps
  • multi_stage_roots_vacuum_pump_acp_90

    Multi-stage roots vacuum pumps

    High pumping speed at low pressures – ideal for demanding rough vacuum processes.

    Multi-stage roots pumps
  • asm_390_392_leak_detector

    Leak detectors

    Quickly locate even the smallest leaks to ensure system integrity and uptime.

    Leak detectors
  • omnistar_mass_spectrometer

    Mass spectrometers

    Precise gas analysis for advanced research and contamination monitoring.

    Mass spectrometers
  • hicube_neo_rga_stage

    Residual gas analyzers (RGA)

    Monitor gas composition with mass spectrometers in real time to safeguard process stability and purity.

    Residual gas analyzers (RGA)
  • vacuum_chambers

    Vacuum chambers

    Modular or custom-built chambers tailored to experimental needs in R&D.

    Vacuum chambers
  • vacuum_valves_1

    Valves

    For precise flow control and isolation in research-grade vacuum setups.

    Vacuum valves
  • digiline_hpt_1

    Gauges

    Accurate pressure measurement from atmospheric pressure to UHV.

    Vacuum gauges
  • turbo_vacuum_pump_units_hicube

    Vacuum pump units

    Preconfigured plug-and-play systems for fast and flexible lab integration.

    Vacuum pump units
  • pvweb_88__ct_tw_h_open_767x430pix

    Gas abatement systems

    Remove harmful exhaust gases and ensure clean lab air and compliance.

    Gas abatement systems

Enabling technologies for advanced research

Pfeiffer supports the operation and integration of vacuum systems in complex R&D environments. To ensure reliable results, several factors need to be considered early in your setup. These include:

  • a solid understanding of ultra-high vacuum conditions
  • the use of residual gas analysis for system insight
  • and the critical role of leak detection.
  • Ultra-high vacuum (UHV)

    Achieving UHV is a prerequisite for many advancedresearch applications– fromsurface science and electron microscopy to beamline experiments. Creating such conditions requires more than high-performance vacuum pumps - it depends on the right materials, sealing, chamber design, and bake-out processes.

    Pfeiffer provides complete UHV solutions, including optimized pumping systems, clean assembly practices, and engineering expertise to help you reach and maintain ultra-high vacuum levels.

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    Learn more about generating ultra-high vacuum

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  • Leak detection for vacuum systems

    Leaks often exist in seals, flanges, or welds. If left undetected, they can prevent your system from achieving the vacuum levels needed for research or delay critical experiments – especially under high and ultra-high vacuum conditions. Fast and reliable localization is therefore essential to ensure system readiness.

    Pfeiffer supports you with helium-based leak detection solutions, including the spraying method, to ensure your system is tight, clean, and ready for operation.

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    Explore our vacuum leak detection solutions

    pvweb_221_allapplicationmotifs_1200x675_001_shutterstock_383902150
  • Residual gas analysis (RGA)

    RGA helps you monitor vacuum composition in real time – detecting contamination, outgassing, or unwanted reactions that could affect your results. This insight is vital for stable operation and reproducibility in demanding research.

    RGA systems from Pfeiffer are trusted in university labs and high-precision setups to ensure control, transparency, and confidence in your vacuum environment.

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    Discover our RGA solutions for research

    pvweb_221_allapplicationmotifs_794x390_residual_gas_analysis

FAQ

What role does vacuum technology play in Research & Development?

Vacuum technology is critical in R&D for creating clean, stable environments that isolate experiments from ambient air, water vapor, and reactive gases. This controlled setting enables precise measurements, higher reproducibility, and contamination-free processing. Vacuum systems ensure that experimental results are not compromised by background interference. For example:

  • Particle accelerators require ultra-high vacuum to reduce beam scattering.
  • Plasma research needs vacuum stability during rapid process cycles.
  • Material Science depends on vacuum during coating, etching, and surface analysis.

Pfeiffer Vacuum+Fab Solutions supports these applications by delivering reliable, integrated vacuum equipment – from vacuum pumps and chambers to leak detectors and gas analysis tools.

What are the different vacuum levels and how are they used in R&D?

Vacuum environments are categorized by pressure levels. Each range supports distinct R&D applications: Choosing the right vacuum range is essential for system integrity and experimental reproducibility. Pfeiffer provides solutions across all vacuum ranges.

Vacuum level
Pressure range
Typical applications
Rough vacuum
1013–1 hPa
Glove boxes, filtration, vacuum drying
Medium vacuum
1–10⁻³ hPa
Lyophilization, analytical preparation
High vacuum
10⁻³–10⁻8 hPa
Ultra-High vacuum (UHV)
10⁻8–10⁻¹² hPa
Cryogenics, beamlines, space simulation, surface science, accelerators
Extreme UHV (XHV)
<10⁻¹² hPa
Nuclear/particle physics, astrophysics

How do I select the right vacuum pump for my research?

Selecting a vacuum pump depends on the process type, gas load, and desired pressure range. Consider:

  • Application needs: What vacuum level is required – rough, high, or UHV?
  • Vacuum pump compatibility: Match with the size of the vacuum chamber, gas type, gas loads, and outgassing behavior.
  • Vacuum pump technology:
    Turbopumps for UHV and fast cycle experiments
    ○ Dry backing pumps (like scroll or diaphragm vacuum pumps) for clean, oil-free lab environments
    Rotary vane vacuum pumps for general purposes
    Vacuum boosters for accelerating the evacuation of large volumes or handling high gas loads

Use our online
Vacuum Calculator to compare pump types, explore performance curves, and configure your ideal system in minutes.

Want guidance? Watch our vacuum pump selection webinar - "The Perfect Match: How to Find the Vacuum Pump for Life" - to better understand vacuum technologies and application fit.

In addition, our vacuum specialists are ready to help configure the best vacuum system for your R&D setup.

Contact us

How can I keep my vacuum system clean and reliable for sensitive experiments?

If you are working in high or ultra-high vacuum, keeping your vacuum system clean and leak-tight is not just nice to have – it is essential. Here are a few tips to help you stay on track:

Start clean, stay clean

  • Always wipe down components before installing them – get rid of fingerprints, oils, and dust.
  • Skip the vacuum grease if you can. Metal seals (like CF flanges) are usually the better choice.
  • Use powder-free gloves when handling anything that goes into the system.

Do not skip the bake-out
  • If you are aiming for UHV, bake your system before use. This drives out moisture and reduces outgassing.
  • Depending on the setup, go up to 300 °C – slowly and under vacuum for best results.

Use the right materials
  • Go for low-outgassing materials and smooth finishes. Avoid anything porous or plastic unless it is rated for vacuum use.
  • Metal-sealed components give you more long-term stability, especially if your system is running 24/7.

Watch for hidden leaks

Calibrate, do not guess

  • Check your vacuum gauges regularly because drift can sneak up on you.
  • Make sure your pressure readings and actual system performance still match.

These small steps go a long way toward keeping your setup stable, your data clean, and your downtime minimal.

Can Pfeiffer Vacuum+Fab Solutions deliver tailored vacuum systems for complex R&D projects?

Absolutely. Whether you are running experiments in a university lab, developing prototypes in advanced manufacturing, or working on beamline setups in particle physics – custom-fit matters.

Pfeiffer develops vacuum systems that are tailored to your exact process needs and integration constraints. From early-stage concepts to fully engineered systems, our experts work closely with scientists, engineers, and technical leads across research institutions and industrial departments to develop vacuum technology that truly fits.

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What does vacuum technology enable in material science research?

Material science relies heavily on vacuum conditions to study surfaces, grow thin films, and analyze material behaviors at the atomic level. Whether you are conducting sputtering, CVD, or advanced microscopy, maintaining clean, stable vacuum systems is essential for reproducibility and precision.

Our systems support:

  • Surface and thin film analysis (XPS, AES, STM)
  • Clean deposition environments (PVD, ALD)
  • Plasma-enhanced processes and coatings

With optimized vacuum pumps, chambers, and real-time instrumentation, Pfeiffer helps researchers push the limits of what materials can do.

How do solutions from Pfeiffer support vacuum testing and quality assurance in research?

Vacuumtesting is not just for system validation. It is critical for maintaining process integrity in high-precision applications like photonics, space simulation, and plasma research. We offer:


These tools help reduce downtime, catch issues early, and ensure compliance with quality standards.

Where does innovation happen with vacuum technology and who is driving it?

Innovation in vacuum technology does not come from one sector alone. It happens across a wide range of industries and research areas, driven by scientists, engineers, and production teams tackling complex challenges every day.

Here is where our solutions help innovation move forward:

  • Aerospace & space technologies
    For testing satellites, simulating orbital conditions, and pushing new materials in extreme environments
  • Pharma & life sciences
    For contamination-free environments in freeze drying, sterile packaging, and protein crystallization
  • University labs & national research centers
    Where fundamental discoveries in material science, plasma physics, or surface analysis are made
  • Semiconductor & advanced manufacturing
    Supporting precision production with fast, stable, and integrated vacuum setups

Whatever your sector, we help you bridge the gap between concept and implementation, combining vacuum expertise with real-world application needs.

Why choose Pfeiffer for your research needs?

As a company focused on enabling innovation across industries, Pfeiffer offers not just high-end products, but a real advantage in configuring and scaling vacuum systems. Whether you are a student, scientist, or advanced user, our solutions meet you where your market demands are.

Start with the vacuum fundamentals or gain expert insights.

Videos basics of vacuum